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Program

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12:00 - 14:00
12:00 - 14:00
Registration
14:00 - 14:15
14:00 - 14:15
Welcome Note
Jan Rupp | University of Lübeck, Lübeck
14:15 - 15:15
14:15 - 15:15
Opening Lecture
Chair: Jan Rupp | University of Lübeck, Lübeck
Exploring the Drivers of Predominant Bacteria Across One Health Domains to Combat AMR
Katharina Schaufler | Helmholtz Institute for One Health, Greifswald
15:15 - 16:15
15:15 - 16:15
Workshop
"Networking at conferences and events"
Moderation: Paul Charlton | German Center for Infection Research, Garmisch-Partenkirchen
16:15 - 16:30
16:15 - 16:30
Coffee Break
16:30 - 17:45
16:30 - 17:45
Presentation of DZIF fellowship holders
Chair: David Tobys | University Hospital Cologne, Cologne
16:30
16:30
A glycan-sensitive ORF2-ELISA and humoral immunity analysis in a large Hepatitis E virus cohort reveal determinants of chronicity
Jonathan Garn | Hannover Medical School (MHH), Hannover
16:45
16:45
Impact of Hepatitis E Virus Variants on Cell Tropism and Antiviral Therapy: Evidence of Extrahepatic Replication and Genomic Signatures
Patrick Behrendt | Hannover Medical School (MHH), Hannover
17:00
17:00
Treatment response to bulevirtide is linked to amelioration of portal hypertension in patients with chronic hepatitis D
Lisa Sandmann | Hannover Medical School (MHH), Hannover
17:15
17:15
Patient-Derived Hepatocyte Organoids as a Translational Model for Adenovirus Pathogenesis
Kevin Paul | University Medical Center Hamburg-Eppendorf (UKE), Hamburg
17:30
17:30
Recombinant Hepatitis B Virus Particles – Generation and Applications
Jochen Wettengel | Technical University of Munich, München
17:45 - 18:45
17:45 - 18:45
TTU Emerging Infections
Chair: Rosanne Sprute | University Hospital Cologne, Cologne
17:45
17:45
Emerging Viruses – Quo Vadis? From Molecular Diagnostics to Targeted Intervention Strategies
Marylyn Addo | University Medical Center Hamburg-Eppendorf (UKE), Hamburg
18:15
18:15
Molecular Virology of Emerging Viruses
Toni Meister | University Medical Center Hamburg-Eppendorf (UKE), Hamburg
18:45
18:45
Dinner
08:30 - 09:30
08:30 - 09:30
Presentation of DZIF fellowship holders
Chair: Vincent Jörg | University Medical Center Hamburg-Eppendorf (UKE), Hamburg
08:30
08:30
Targeting Intracellular Bacterial Reservoirs to Improve the Treatment of Urinary Tract Infections (UTIs)
David Tobys | University Hospital Cologne, Cologne
08:45
08:45
Phages for a holistic therapy of recurrent urinary tract infections (rUTI)
Simone Lieberknecht | University Hospital Frankfurt, Frankfurt am Main
09:00
09:00
Gut Resistome and Resistance Evolution in E. coli Urinary Tract Infections After Kidney Transplantation
Kaan Koçer | University of Lübeck, Lübeck
09:15
09:15
Deciphering the antibody response against Candida virulence factors
Rosanne Sprute | Hannover Medical School (MHH), Hannover
09:30 - 10:30
09:30 - 10:30
TTU Hepatitis
Chair: Veronica Ober | LMU University Hospital Munich, Munich
09:30
09:30
TTU Hepatitis: Towards cure and prevention of hepatotropic viral infections
Lena Allweiss | University Medical Center Hamburg-Eppendorf (UKE), Hamburg
10:00
10:00
Translation and Back-Translation: How a clinical study within the TTU Hepatitis allows the optimization of patient treatment.
Helenie Kefalakes | Hannover Medical School (MHH), Hannover
10:30 - 11:00
10:30 - 11:00
Coffee Break
11:00 - 12:00
11:00 - 12:00
TTU Malaria and Neglected Tropical Diseases
Chair: Simone Lieberknecht | University Hospital Frankfurt, Frankfurt am Main
11:00
11:00
Loiasis
Michael Ramharter | Bernhard Nocht Institute for Tropical Medicine (BNITM), Hamburg
11:30
11:30
Antimalarials for the treatment of schistosomiasis
Johannes Mischlinger | Bernhard Nocht Institute for Tropical Medicine (BNITM), Hamburg
12:00 - 13:00
12:00 - 13:00
Lunch
13:00 - 15:00
13:00 - 15:00
Networking Event: Guided Tour through the Lübeck Holstentor
Discover Lübeck’s most famous landmark! During this guided tour, participants will explore the historic Holstentor and learn about the city’s rich Hanseatic past. Enjoy fascinating insights into Lübeck’s medieval architecture and its significance as a UNESCO World Heritage site.
15:00 - 15:30
15:00 - 15:30
Flash Talks
Chair: Lisa Göpel | University Hospital Schleswig-Holstein (UKSH), Lübeck
1
1
From Gamete fusion to intervention: evaluating the transmission blocking vaccine target Hap2 in Plasmodium
Djamila Aschrafi | Heidelberg University, Heidelberg
2
2
CRIP1 as a key mediator linking infection-induced inflammasome activation to hypertension
Jorge Duque Escobar | University of Lübeck, Lübeck
3
3
Genomic and phenotypic insights into a globally expanded clone of Chlamydia pneumoniae
Kensuke Shima | University Hospital Schleswig-Holstein (UKSH), Lübeck
4
4
Genomic sequencing-based hybrid characterization of Schistosoma sp. worms from clinical cohorts- GENOSCHIS
Piyas Mukherjee | Technical University of Munich (TUM), Munich
5
5
Characterizing TLR-mediated immunosenescence in chronic viral infections
Aarushi Nair | University of Heidelberg
6
6
Biophysical characterization of bocaparvovirus gene therapy vectors
Linda Luise Ruck | University of Heidelberg
15:30 - 17:00
15:30 - 17:00
Coffee Break & Poster Session
Poster walk
17:00 - 18:30
17:00 - 18:30
Workshop
"Advanced Clinician Scientist in DZIF"
Moderation: Lisa Sandmann | Hannover Medical School (MHH), Hannover & Patrick Behrendt | Hannover Medical School (MHH), Hannover
18:30
18:30
Dinner
08:30 - 09:30
08:30 - 09:30
Insights of the DZIF Patient Advisory Board
Chair: Jan Rupp | University of Lübeck
Speaker: Marc Franke & Cordula Ehlers | DZIF Patient Advisory Board Germany
09:30 - 10:15
09:30 - 10:15
Presentation of DZIF fellowship holders
Chair: Kevin Paul | University Medical Center Hamburg-Eppendorf (UKE), Hamburg
09:30
09:30
Fusobacterium nucleatum derived 2-hydroxybutyric acid promotes nrf2-associated carcinogenesis in colorectal cancer
My-Lan Pianka | Heidelberg University Hospital, Heidelberg
09:45
09:45
Staphylococcus epidermidis colonization, bacteriophages and immune trajectories in preterm infants
Janina Marißen | University Hospital Würzburg, Würzburg
10:00
10:00
Non-tuberculous infections in Gabon - a multidisciplinary study of a clinical cohort, recombinant paragonimiasis serology development and wildlife surveys
Stefan Fabian Weber | Heidelberg University, Heidelberg
10:15 - 10:45
10:15 - 10:45
Coffee Break
10:45 - 11:45
10:45 - 11:45
TTU Community-Acquired Infections at Mucosal Interfaces
Chair: My-Lan Pianka | Heidelberg University Hospital, Heidelberg
10:45
10:45
Community-Acquired Infections at Mucosal Interfaces
Benjamin Heidrich | Hannover Medical School (MHH), Hannover
11:15
11:15
H. pylori Infection: Diagnostic, Preventive and Therapeutic Approaches to Optimize Clinical Management
Riccardo Vasapolli | LMU University Hospital Munich, Munich
11:45 - 12:45
11:45 - 12:45
Presentation of DZIF fellowship holders
Chair: Janina Marißen | University Hospital Würzburg, Würzburg
11:45
11:45
CXCR5 Anti-Env CAR T Cells Targeting HIV-Infected Cells in Peripheral Blood and Secondary Lymphoid Tissue
Veronica Ober | LMU University Hospital Munich, Munich
12:00
12:00
Identification of a broad and potent V3 glycan site bNAb targeting an N332gp120 glycan-independent epitope
Lutz Gieselmann | University Hospital Cologne, Cologne
12:15
12:15
Expression analysis of co-inhibitory molecules PD-1, TIGIT, TIM-3 and LAG-3 in acute P. falciparum infections – a cohort study
Vincent Jörg | University Medical Center Hamburg-Eppendorf (UKE), Hamburg
12:30
12:30
Comparison of the clinical and immune-controlled characteristics of hepatocellular carcinoma caused by HBV and HDV
Anika Wranke | Hannover Medical School (MHH), Hannover
12:45 - 13:00
12:45 - 13:00
Closing Remarks
Jan Rupp | University of Lübeck
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