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DZIF Academy 2022

9th Translational DZIF-School

September 28-30, 2022 | Lübeck, Hotel Atlantic

Dear Colleagues and Friends, 

It is my pleasure and privilege to invite you to join the 9th Translational DZIF School, which will be held in presence in Lübeck from 28th to 30th September 2022. With a special focus on translational science we aim to bring together clinical and basic researchers (PhDs, PostDocs and junior group leaders) to discuss latest developments in Infectious Diseases and Clinical Microbiology. In this year´s program major findings from the thematic translational units Infections of the Immunocompromised Host, Healthcare-associated and Antibiotic-resistant Bacterial Infections, HIV, Novel Antibiotics and Tuberculosis will be presented. In addition, DZIF clinical leave and MD/PhD stipendiaries will present their work in separate sessions to explore their data with established researchers in the field. Furthermore, all other participants will be given the possibility to present their work within the scope of a poster session.

I am looking forward to share with you some exciting days in Lübeck, learning from each other in the dynamic and fastidious field of Infectious Diseases Research.

See you in Lübeck!

Best regards

Prof. Dr. med. Jan Rupp
Director
Department of Infectious Diseases and Microbiology
University of Lübeck

Prof. Dr. med. Jan Rupp

Program 2022

12:00 - 14:00
12:00 - 14:00
Registration
14:00 - 14:15
14:00 - 14:15
Welcome Note
Jan Rupp | University of Lübeck
14:15 - 15:15
14:15 - 15:15
Opening Lecture
Chair: Jan Rupp | University of Lübeck
Bacteria-bacteria killing in microbial communities
Daniel Unterweger | Max-Planck-Institut für Evolutionsbiologie Plön
15:15 - 16:15
15:15 - 16:15
TTU Tuberculosis
Chair: Martin Demmert | UKSH Campus Lübeck
Drug Discovery and Development: Traditional approaches and novel opportunities
Norbert Reiling and Christoph Hölscher | Forschungszentrum Borstel
16:15 - 16:30
16:15 - 16:30
Coffee Break
16:30 - 17:00
16:30 - 17:00
Workshop
Presenting Skills: Slide design, sequence & build
Paul Charlton | DZIF
17:00 - 17:30
17:00 - 17:30
Presentation of DZIF stipendiats
Chair: Jakob Malsy | University Hospital Hamburg-Eppendorf
17:00
17:00
Infectious complications in pediatric oncology - characterization of immune- and microbiome signatures in mucositis and febrile neutropenia
Martin Demmert | UKSH Campus Lübeck
17:15
17:15
Bacterial sialidases: Interactions between the biliary microbial community and Cholangiocytes
Freya Wellhöner | Medizinische Hochschule Hannover
17:30 - 18:30
17:30 - 18:30
TTU HIV
Chair: Alexandros Hadjilaou | University Hospital Hamburg-Eppendorf
17:30
17:30
Finished and pending duties 40 years after the discovery of HIV
Georg Behrens | Medizinische Hochschule Hannover
18:00
18:00
Broadly neutralizing antibodies for treatment and prevention of HIV-1 infection
Philipp Schommers | University Hospital Cologne
18:30
18:30
Get together
08:30 - 09:30
08:30 - 09:30
Presentation of DZIF stipendiats
Chair: Freya Wellhöner | Medizinische Hochschule Hannover
08:30
08:30
Characterization of CD4+ T cells in chronic hepatitis D virus infection: preliminary work and project outline
Helenie Kefalakes | Medizinische Hochschule Hannover
08:45
08:45
A novel class of glycan-sensitive human monoclonal antibodies neutralizing the hepatitis E virus
Katja Dinkelborg | Medizinische Hochschule Hannover
09:00
09:00
CIDP: an extrahepatic manifestation of hepatitis E virus (HEV) infections
Sven Pischke | University Hospital Hamburg-Eppendorf
09:15
09:15
Advancing (bio)analytic tools for the prediction of synergistic drug combinations for tuberculosis therapy
Anna-Cathrine Neumann-Cip | LMU München
09:30 - 10:30
09:30 - 10:30
TTU Infections of the Immunocompromised Host
Chair: Janina Kühlwein | Universität Bonn
09:30
09:30
Infections of the Immunocompromised Host
Daniel Depledge | Medizinische Hochschule Hannover
10:00
10:00
Human Cytomegalovirus pUL11: a T cell modulator and possible new therapeutic target
Penelope Kay-Fedorov | Medizinische Hochschule Hannover
10:30 - 11:00
10:30 - 11:00
Coffee Break
11:00 - 12:00
11:00 - 12:00
TTU Novel Antibiotics
Chair: Annika Claßen | University Hospital Cologne
Towards translation of the pathoblocker principle: the path from target identification to candidate selection of quorum sensing inhibitors against Pseudomonas aeruginosa infections
Martin Empting | Helmholtz-Zentrum für Infektionsforschung Braunschweig
12:00 - 13:00
12:00 - 13:00
Lunch
13:00 - 14:00
13:00 - 14:00
Workshop
Advanced Clinician Scientist in DZIF
Helenie Kefalakes | Medizinische Hochschule Hannover and Sven Pischke | University Hospital Hamburg-Eppendorf
14:00 - 14:30
14:00 - 14:30
Workshop
Presenting Skills: Poster presentations
Paul Charlton | DZIF
14:30 - 15:00
14:30 - 15:00
Flash Talks
Chair: Nadja Käding | University of Lübeck
1
1
Influence of genotype and viral load on the clinical presentation of influenza infection in children
Sarah Klemm | University Hospital Heidelberg
2
2
Commensals versus viruses – how the microbiota influences host susceptibility to viral infections
Raphaël Jami | UK Tübingen
3
3
System-biology approach to find broadly acting antiviral drugs
Maximilian Breitenbach | Institut für medizinische Virologie Tübingen
4
4
A mosquito-transmitted blood-stage attenuated malaria parasite as an experimental vaccine
Luisa Zechel | Center for Infectious Diseases, Heidelberg University Medical School
5
5
Sex differences in the innate immune response after immunization against COVID-19 with MVA-SARS-2-S and/or mRNA vaccines
Marie-Louise Dieck | University Hospital Hamburg-Eppendorf
6
6
Targeting Staphylococcus aureus pore-forming toxins as a strategy to identify new anti-infectives
Virginia Njau | Helmholtz Centre for Infection Research Braunschweig
7
7
Diverse activation of human neutrophils caused by different isolates of C. pneumoniae
Hendrik Jansen | University of Lübeck
8
8
Intrapartum antibiotic administration: impact on the infant’s gut microbiome and resistome development
Mariia Lupatsii | University of Lübeck
9
9
Exploring the spread of antimicrobial resistances along the gut-lung-axis
Max Moll | University of Lübeck
10
10
Genotype and knowledge-based approach to predict antimicrobial resistance in the opportunistic pathogens Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli
Carolina Mastella Botelho | Twincore/ MHH/ HZI Hannover
15:00 - 16:30
15:00 - 16:30
Poster Session and Coffee
Poster walk
16:30 - 17:30
16:30 - 17:30
Workshop
Networking at a conference
Paul Charlton | DZIF
18:00 - 19:30
18:00 - 19:30
Networking Event
Guided tour through the Hansemuseum
19:30
19:30
Dinner
08:30 - 09:30
08:30 - 09:30
Keynote Lecture
Chair: Jan Rupp | Universität zu Lübeck
Host-microbiome interactions in the context of industrialization
Mathieu Groussin | Universität Kiel
09:30 - 10:30
09:30 - 10:30
TTU Healthcare-associated and Antibiotic-resistant Bacterial Infections
Chair: Anna-Cathrine Neumann-Cip | LMU München
09:30
09:30
Healthcare-associated antibiotic-resistant bacterial infections
Dennis Nurjadi | University of Lübeck
10:00
10:00
In vitro Evaluation of a Newly Designed Bacteriophage Cocktail as Potential Approach for Prophylactic Selective Digestive Decontamination of ESBL Escherichia coli in High-Risk Cancer Patients – Results of the IDEAL-EC study
Annika Claßen | University Hospital Cologne
10:30 - 11:00
10:30 - 11:00
Coffee Break
11:00 - 12:30
11:00 - 12:30
Presentation of DZIF stipendiats
Chair: Helenie Kefalakes | Medizinische Hochschule Hannover
11:00
11:00
Automation of histological analysis of onchocerciasis nodules with Artificial intelligence (AI)
Janina Kühlwein | University Hospital Bonn
11:15
11:15
Infiltrative monocyte-derived adenosine deaminase function in host defense against SARS-CoV-2
Shilpa Tiwari-Heckler | Universität Heidelberg
11:30
11:30
SARS-CoV-2 specific cellular response following three COVID-19 vaccinations in patients with chronic lymphocytic leukemia
Sibylle Mellinghoff | University Hospital Cologne
11:45
11:45
Genomic characterization of bat pneumovirus
Wendy Karen Jo Lei | Charité Berlin
12:00
12:00
Human Norovirus infection of human intestinal organoids: Innate immune response and its sex-specific regulation
Jakob Malsy | University Hospital Hamburg-Eppendorf
12:15
12:15
Brain endothelial programmed cell death in cerebral malaria
Alexandros Hadjilaou | University Hospital Hamburg-Eppendorf
13:00
13:00
Closing Remarks
Jan Rupp | University of Lübeck
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