5th Translational DZIF-School

22–24 November 2017 • Lübeck, Germany

5th Translational DZIF-School

22–24 November 2017 • Lübeck, Germany

Congress details

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Poster Session

Thursday, 23 November 2017
15:00-16:30 

P1
Dynamics of TLR2 ligand synthesis by Orientia tsutsugamushi
Véronique Hefter1, Zacharias Orfanos1, Christian Keller1
1Philipps-Universität Marburg, Institut für Virologie, Marburg, Germany 

P2
HIF-1α drives fungal immunity in human macrophages
Dirk Friedrich1, Björn Lohse1, Dorinja Zapf1, George S. Deepe2, Jan Rupp1
1University of Lübeck, Department of Infectious Diseases and Microbiology, Lübeck, Germany
2University of Cincinnati, Department of Medicine, Division of Infectious Disease, University of Cincinnati, Cincinnati, United States 

P4
"Ex-vivo double-hit BPD model" for tissue-specific lung immunity in preterm infants
Nele Twisselmann1, Julia Pagel1, Christoph Härtel1
1University of Lübeck, Klinik für Kinder- and Jugendmedizin, Lübeck, Germany 

P3
Effect of the first-choice antimicrobials on the metabolism of C. trachomatis infected host cells
Nis Schmidt1,2, Maximilian Wanker1,2, Nadja Käding1, Kensuke Shima1, Jan Rupp1,2
1University of Lübeck, Department of Infectious Diseases and Microbiology, Lübeck, Germany
2German Center for Infection Research (DZIF), Hamburg-Borstel-Lübeck, Germany 

P5
Suppressive capacity of PMN-MDSC is lost in advanced stages of HIV-1 infection

Eva Grützner1, Ashley Neizert1, Renate Stirner1, Raffele Conca2, Immanuel Andrä3, Matthias Schiemann3, Christoph Klein2, Ulrike Protzer4, Johannes Bogner1, Rika Draenert1
1Klinikum der Ludwig-Maximilian Universität München, Sektion Infektiologie Med. Klinik und Poliklinik IV, München, Germany
2Kinderklinik und Kinderpoliklinik der Ludwig Maximilian Universität München, Dr. von Haunersches Kinderspital, München, Germany
3Technische Universität München, Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, München, Germany
4Technische Universität München, Institut für Virologie, München, Germany

P6
The HIV observational database software, HIObs

Barbara Bartmeyer1, Christian Kollan1, Daniel Schmidt1, Eberhardt Pape1, Hermann Claus1, Andrea Kühne1, Viviane Bremer1, Osamah Hamouda1, Gerd Fätkenheuer1,2, Stephanie Heinen1,2, Jörg Janne Vehreschild1,2
1Robert Koch Institute, Dept. of Infectious Disease Epidemiology , Berlin, Germany
2University hospital of Cologne, Clinic I for Internal Medicine , Cologne, Germany 

P7
Phylogenetic and Immunologic Investigation on the 2015/2016
Outbreak of Scrub Typhus in Nepal

Nora En-Nosse1, Anurag Adhikari2, Zacharias Orfanos1, Christian Keller1
1Institute of Virology, Philipps University Marburg, Germany
2Kathmandu Research Institute for Biological Sciences, Kathmandu, Nepal

P8
Investigation of new potential protein synthesis inhibitors from Streptomycetes of the 'Tübinger strain collection'
Franziska Handel1, Katharina Wex2, Wolfgang Wohlleben1, Yvonne Mast1
1University of Tübingen, Interfacultary Institute for Microbiology and Infection Medicine Tübingen (IMIT), Microbiology / Biotechnology, Tübingen, Germany
2University of Tübingen, Interfacultary Institute for Microbiology and Infection Medicine Tübingen (IMIT), Microbial Bioactive Compounds, Tübingen, Germany 

P9
A novel antibiotic for the treatment of chlamydial infections
Nathalie Loeper1, Simon Graspeuntner1, Svea Ledig1, Inga Kaufhold1, Friederike Hoellen2, Andrea Schiefer3,4, Kenneth Pfarr3,4, Achim Hörauf3,4, Kensuke Shima1, Jan Rupp1,5
1University of Lübeck, Department of Infectious Diseases and Microbiology, Lübeck, Germany
2University Hospital of Schleswig-Holstein, University of Lübeck, Department of Obstetrics and Gynecology, Lübeck, Germany
3University of Hospital Bonn, Institute of Medical Microbiology, Immunology and Parasitology, Bonn, Germany
4German Center for Infection Research (DZIF), partner site Bonn-Cologne, Bonn, Germany
5German Center for Infection Research (DZIF), partner site Hamburg-Lübeck-Borstel, Lübeck, Germany 

P10
Deciphering the modes of action of novel antibiotics against Pseudomonas aeruginosa by comparison of proteomic signatures
Dominik Wüllner1, Maren Gesper1, Christoph H. R.  Senges1, Annika Haupt1, Ben Struck1, Julia E. Bandow1
1Ruhr-Universität Bochum, Applied Microbiology, Bochum, Germany 

P11
Neutrophil associated proteins as potential signatures for point-of-care diagnostic and putative targets for host-directed-therapy in tuberculosis.

Christoph Leschczyk1, Tobias Dallenga1, Kollipara  Laxmikanth2, Vivian Sparr1, Barbara Kalsdorf3, Albert  Sickmann2, Ulrich E. Schaible1
1Research Center Borstel, Cellular Microbiology, Borstel, Germany
2Leibniz-Institut für Analytische Wissenschaften, Dortmund, Germany
3Resarch Center Borstel, Clinical Infectious Diseases, Borstel, Germany 

P12
Novel approach to capture and enrich Mycobacterium tuberculosis and its DNA from saliva

Julia Hansen1, K. Kolbe1, S. Malm2, J. Zallet3, Hillemann3, K. H. Wiesmüller4, J. Brandenburg1, C. Herzmann5, N. Reiling1
1Leibniz Center for Medicine and Biosciences, Microbial Interface Biology, Research Center Borstel, Borstel, Germany
2Leibniz Center for Medicine and Biosciences, Molecular and Experimental Mycobacteriology, Research Center Borstel, Borstel, Germany
3Leibniz Center for Medicine and Biosciences, National Reference Center, Research Center Borstel, Borstel, Germany
4EMC microcollections GmbH, Tübingen, Germany
5Leibniz Center for Medicine and Biosciences, Center for Clinical Studies, Research Center Borstel, Borstel, Germany