5th Translational DZIF-School

22–24 November 2017 • Lübeck, Germany

5th Translational DZIF-School

22–24 November 2017 • Lübeck, Germany

Congress details

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Key topics

  • Emerging Infections
  • Tuberculosis
  • HIV
  • Healthcare-associated and Antibiotic-resistant bacterial Infections
  • Novel Antibiotics
12:00 – 14:00 Registration
14:00 – 14:15 Welcome Note
Jan Rupp (Lübeck)
14:15 – 15:15
Chair
Welcome Lecture
Jan Rupp (Lübeck)
Antibiotic consumption and resistance in Germany
Michael Kresken (Rheinbach)
15:15 – 15:45
Chair
Presentation of DZIF stipendiats
Julia Pagel (Lübeck)
15:15
O1
Characterization of immune response against Malaria
Aurore Bouyoukou Hounkpatin (Tübingen)
15:30
O2
Pathophysiology of delayed haemolysis and mechanisms of clearance of pitted erythrocytes
Katrin Scheu (Hamburg)
15:45–16:00 Coffee break
16:00 – 17:00
Chair
TTU Emerging Infections
Felix Stahl (Hamburg)
16:00 The rVSV-vaccine platform: Comprehensive analysis of immunogenicity against Ebola GP following rVSV-vectored Ebola vaccination
Christine Dahlke (Hamburg)
17:00 – 18:00
Organizers
Workshop 1: Product Development Unit
Ivana Skrnjug, Jens Reinhardt (Langen)
Regulatory and project management support for DZIF scientists: Tools and examples
from 18:30 Dinner
08:30 – 09:30
Chair
DZIF Academy
Julian Schwarz (Tübingen)
08:30 Translational research on neglected infectious diseases – Challenges and perspectives
Christian Keller (Marburg)
09:30 – 10:30
Chair
TTU Healthcare-associated and antibiotic-resistant bacterial infections
Thomas Michler (Munich)
09:30 Can we avert the post-antibiotic era? Concepts from the TTU HAARBI
Jörg-Janne Vehreschild (Cologne)
10:30 – 11:00 Coffee break
11:00 – 11:30
Chair
TTU Healthcare-associated and antibiotic resistant bacterial infections
Thomas Michler (Munich)
11:00 Breaking the vicious cycle of antibiotic abuse and multi-resistance – Cluster intervention in 5 German Tertiary Care Centers
Annika Löhnert (Cologne)
11:30 – 12:30
Chair
Presentation of DZIF stipendiats
Paul Wratil (Munich)
11:30
O3
MERS Vaccine development: Update on the Phase I First-in-human MVA-MERS-S trial
Till Koch (Hamburg)
11:45
O4
RNA interference mediated suppression of Hepatitis B virus improves the induction of CD8+ T cell responses by therapeutic vaccination
Thomas Michler (Munich)
12:00
O5
Multimodal assessment of inflammatory mediators of intrahepatic cells and peripheral
blood mononuclear cell subsets in chronic Hepatitis B virus infection
Jan-Hendrik Bockmann (Hamburg)
12:15
O6
Increased expression of the co-inhibitors PD-1 and BTLA on CMV-specific T-cells is associated with symptomatic CMV infection in renal transplant patients
Meike Kaulfuß (Essen)
12:30 – 13:30 Lunch break
13:30 – 15:00
Chair
TTU HIV
Aurore Bouyoukou Hounkpatin (Tübingen)
13:30 HIV-1 Infection: The role of the gastrointestinal tract
Clara Lehmann (Cologne)
14:10 Discussion
14:30 Together competitive – The translational platform HIV
Jörg-Janne Vehreschild (Cologne)
14:50 Discussion
15:00 – 16:30 Coffee break and Poster session
16:30 – 17:30
Chair
TTU Novel Antibiotics
Till Koch (Hamburg)
16:30 Discovery of novel lead structures from natural sources to combat multiresistant bacterial pathogens?
Marc Stadler (Braunschweig)
16:50 Discussion
17:00 The steps to take after discovery of antibiotic efficacy - preclinical development of the novel antibiotic Corallopyronin A
Kenneth Pfarr (Bonn)
17:20 Discussion
17:30–18:30
Organizer
Workshop 2: Epidemiology
Gérard Krause (Braunschweig)
Epidemiological Research in DZIF – First experiences and accomplishments of the new translational infrastructure epidemiology
18:30–19:30 Dinner
from 19:45 Guided tour through the European "Hansemuseum"
08:30 – 09:30
Chair
Presentation of DZIF stipendiats
Jan-Hendrik Bockmann (Hamburg)
08:30
O7
Validation of oral rapid HIV test among children in Harare, Zimbabwe: a case report
Franziska Freinberger (Borstel)
08:45
O8
Antibody-mediated therapy of HIV-1 infection
Henning Grüll (Cologne)
09:00
O9
The role of HLA-F in HIV-1 infection
Angelique Hölzemer (Cologne)
09:15
O10
SAMHD1 – Biological role and modulation of its enzymatic function
Paul Wratil (Munich)
09:30 – 10:30
Chair
DZIF Academy Faculty Lecture Session
Henning Grüll (Cologne)
09:30 Negotiation skills for scientists
Paul Charlton (Munich)
10:30 – 11:00 Coffee break
11:00 – 12:00
Chair
Presentation of DZIF stipendiats
Angelique Hölzemer (Hamburg)
11:00
O11
Antiviral mechanisms in pre- and postnatal cytomegalovirus infection
Felix Stahl (Hamburg)
11:15
O12
Course of myeloid-derived suppressor cells (MDSC) during the neonatal period in human and mice
Julian Schwarz (Tübingen)
11:30
O13
Distinct development of intestinal microbiota influenced by probiotics decreases risk of necrotizing enterocolitis in preterm infants
Julia Pagel (Lübeck)
11:45
O14
Chronic pulmonary impairment and associated risk factors after active TB disease
Andrea Rachow (Munich)
12:00 – 13:00
Chair
TTU Tuberculosis
Andrea Rachow (Munich)
12:00 Translation tuberculosis research
Stefan Niemann (Borstel)
12:20 Discussion
12:30 Neutrophils as targets for host-directed therapy against tuberculosis
Tobias Dallenga (Borstel)
12:50 Discussion
13:00 Closing remarks